The track category is the heading under which your abstract will be reviewed and later published in the conference printed matters if accepted. During the submission process, you will be asked to select one track category for your abstract.
- Track 1-1Protein Folding
- Track 1-2Molecular Modeling
- Track 1-3Computational Biology
- Track 1-4Drug Design
- Track 1-5Protein Dynamics
Molecular biology is a branch of biology that deals with the process of replication, transcription, translation and cell function. The centre of attraction is where DNA creates RNA and RNA creates protein. By applying the principles of biology, chemistry, and engineering, we can create plenty of chemicals, antibodies, proteins, and enzymes in a better manner. This leads the molecular biology into various disciplines like agricultural molecular biology, medical or pharmaceutical molecular biology, industrial molecular biology and environmental molecular biology.
- Track 2-1Post Translational Modification
- Track 2-2Sequence Alignment
- Track 2-3Genome Assembly
- Track 2-4Transcription
- Track 2-5Next gen Sequencing
- Track 2-6RNA Based Genomes
- Track 2-7Protein folding and misfolding
Biochemistry closely related to molecular biology , the study of molecular mechanisms by which genetic information encoded in DNA is able to result in the process of life. Biochemistry deals with the structures, function and interactions of biological macromolecules such as proteins, nucleic acids, carbohydrates and lipids. The chemistry also depends upon reaction of smaller molecules and ions. The finding of biochemistry primarily applied in medicine, nutrition and agriculture. In medicine biochemist investigate the causes and cure of diseases. In nutrition , they show how to maintain health wellness and study the effects of nutritional deficiencies. In agriculture biochemist investigate soil and fertilizers and try to discover ways to improve crop cultivation, crop storage and pest control.
- Track 3-1Biomolecules
- Track 3-2Metabolism
- Track 3-3Genetic Engineering
- Track 3-4Gene Therapy
- Track 3-5Molecular chemistry
- Track 3-6Animal Biochemistry
- Track 3-7Plant Biochemistry
Bioinformatics is the use of computers for the acquisition , management and analysis of biological information. It incorporates elements of molecular biology, database computing and internet. Bioinformatics is clearly a multi-disciplinary field including computer system management networking, database design, computer programming, computational biology, statistics, mathematics, genetics and molecular biology. The analysis of DNA sequence data has come to dominate the field of bioinformatics , but the term has been applied to any type of biological data that can be recorded as number or images and handled by computers. Bioinformatics enhance protein structure analysis, gene and protein functional information, data from patents, pre-clinical and clinical trials and the metabolic pathways of numerous species.
- Track 4-1Analysis of gene expression
- Track 4-2Analysis of regulation
- Track 4-3Analysis of mutation in cancer
- Track 4-4Comparative genomics
- Track 4-5High throughput image analysis
Biotechnology is the application of scientific technique to modify and improve plants, animals and microorganisms to enhance their value. Biotechnology allows for the manipulation, synthesis and eventual creation of genes. Depending on the tools and application on the biotechnology field often overlaps with the molecular biology, bioengineering, biomedical engineering, bioinformatics , biomanufacturing and molecular engineering. Two important techniques developed in modern technology is genetic engineering and chemical engineering. Genetic engineering is the technique of removing, modifying and adding of genes to a DNA molecule in order to change in the information. By changing the information, genetic engineering changes the amount of proteins an organism is capable of producing. Chemical engineering science utilizes mass momentum and energy transfer along with thermodynamics and chemical kinetics to analyse and improve these unit operations.
- Track 5-1Chemical Engineering
- Track 5-2Genetic Engineering
- Track 5-3Protein Engineering
- Track 5-4Pharmacology
- Track 5-5Nano Biotechnology
- Track 5-6Bioinformatics
- Track 5-7Chemical Engineering
Molecular Modeling define as theoretical methods and computational techniques use to mimic the behaviour of molecules and molecular systems. Modeling helps the scientist to visualize molecules to discover new compounds on drugs. In molecular modelling include verification and validation. Verification used to compare the accuracy of the model. Validation process used to compare the experimental measurements for the simulated results and Experimental frames. Molecular Modeling in drug design is performed by the molecular mechanics and quantum mechanics . Molecular mechanics is used for calculation of energy of atoms , force on atoms and their resulting motion. Quantum mechanics provide information about nuclear position and distribution.
- Track 6-1Experimental Frames
- Track 6-2Energy Minimisation
- Track 6-3Verification
- Track 6-4Validation
Drugs have been discovered by identifying the active ingredients from traditional remedies. Drug discovery process contain different methods like Random Screening, Molecular manipulation, Molecular Designing and Drug Metabolites. Target selection in drug discovery is used to define the decision to focus on finding the agents with biological action that is anticipated to have a therapeutic utility. Target identification to identify the target molecules that involved in the disease progression. Target Validation is the process of manipulation the molecular targets that can provide benefits for patients. Assay development in the drug is used to measure the activity of the drug and evaluate the expression of protein targets and Enzyme interactions. Pharmacogenomics studies has been done in the drug discovery process used to identify the phenotype affect to drug response.
- Track 7-1Nanotechnology
- Track 7-2coding for Target Proteins
- Track 7-3Identification
- Track 7-4Analysis
- Track 7-5Pharmacogenomics
- Track 7-6Assay Development
- Track 7-7Drug Target Identification and Validation
Mapping is the process of Visualizing relationship between the different concepts. In Bioinformatics mapping involved in different ways like Gene mapping, Physical mapping, Genome Sequencing. Genome mapping based studies used to construct the maps that showing the position of the genes. Physical mapping mainly used in molecular biology used to examine the DNA molecules and construct the map showing the position of genes and sequencing features. Genome sequencing shows in the process of shot gun sequencing technique used to characterize each fragment and put each fragment into together. Top Down approach is the type of physical mapping was conducted exclusively by using the fingerprinting approach. Physical mapping consists of overlapping large insert clones was first constructed and carefully checked. After constructed the large insert clones the set of mapped clones was chosen that covers the genome with minimum overlap. Then chosen genome was sequenced segment by segment in orderly manner. Bottom up approach exclusively start with whole genome shot gun sequencing and assembling data from sequencing contigs. Mapping strategies used to find the arrangements of contigs in genome.
- Track 8-1Genome Mapping
- Track 8-2Bottom up Approach
- Track 8-3Top Down Approach
- Track 8-4Genome Sequencing
Structural genomics emphasizes high throughput determination in protein structures. The genome based approaches allows for a structural determination by a combination of experimental and Modeling approaches. Structural genomics attempts to determine the structure of every protein encoded by the genome rather than focusing on one particular protein. The importance of structural genomics in understanding the function of proteins and also provide insight in dynamic properties such as protein folding and identify possible targets that may be used for drug discovery. Structural genomics determines in the process of PCR amplification, cloning of coding sequence, expression of protein, sequencing the cloned genes, confirming the expression of protein, NMR measurements and functional annotation.
- Track 9-1Functional Genomics
- Track 9-2Expression of protein
- Track 9-3Determination of protein
- Track 9-4Regulatory elements of proteins
- Track 9-5Protein coding genes
- Track 9-6Whole genome duplication
Protein Engineering can be defined as the modification of protein structure with recombinant technology or chemical treatment to get a desirable function for better use in medicine industry and agriculture. Protein engineering undergoes process like mutagenesis used for modifying proteins, replacements on protein level and mutation in DNA level. It undergoes two strategies for protein engineering like rational protein design and direct evolution of protein. The objectives of protein engineering includes to create a superior enzyme, produce enzyme in large quantities and produce biological compounds like synthetic peptide, storage protein and synthetics drugs.
- Track 10-1Stability and activity of enzyme
- Track 10-2Substrate and reaction specificity
- Track 10-3Cofactor requirements
- Track 10-4Molecular weight and subunit structures
- Track 10-5Selection and determination of recombinant DNA technology
Gene Expression is the process of converting structure and function of the cells by producing biological molecule like protein. In gene expression steps include like transcription, translation, post translational modification. In gene regulation structure and function of cell can be analysed based on cellular differentiation and adaptability of the organism. Mapping Expression patterns which may include translation, transcription which involved in the process of gene expression. translation and transcription which is used to synthesis of the RNA and read the messenger RNA along with specific protein and according to their instructions.
- Track 11-1Correlating Expression Patterns
- Track 11-2Mapping Expression Data
- Track 11-3 Mapping Sequence Data
Cancer gene therapy approaches have benefited greatly from the utilization of molecular-based therapeutics. Of these, adenovirus-based interventions hold much promise as a platform for targeted therapeutic delivery to tumours. However, a barrier to this progression is the lack of native adenovirus receptor expression on a variety of cancer types. As such, any adenovirus-based cancer therapy must take into consideration retargeting the vector to non-native cellular surface receptors. Predicated upon the knowledge gained in native adenovirus biology, several strategies to transductionally retarget adenovirus have emerged. Herein, we describe the biological hurdles as well as strategies utilized in adenovirus transduction targeting, covering the progress of both adapter-based and genetic manipulation-based targeting. Additionally, we discuss recent translation of these targeting strategies into a clinical setting.
- Track 12-1Replication competent gene therapy vectors
- Track 12-2Non replicating gene therapy vectors
- Track 12-3Adenoviral vector
- Track 12-4Identification of therapeutic protein
- Track 12-5Radiation therapy
Transcriptomics is the study of complete set of RNAs which genome encoded in a specific organism under specific set of conditions. Transcriptomics studies shows expression profiling which examines the expression level of MRNAs in each cell by using microarray technology. In transcriptomics the expression level of each transcript changed during drug development process. Technologies used in transcriptomics is hybridization-based approach and sequence-based approaches. Hybridization-based approaches used in two microarray techniques like two-channel microarray and one-channel microarray. Two-channel microarray has two samples with different fluorescent dye. One-channel microarray is based on RNA which has labelled with fluorescent dye and hybridized with single array where millions of copies of all known genes. Hybridization-based approaches used to provide the view of gene expression by changing two or more biological conditions.
- Track 13-1Includes Set of All RNA Molecules
- Track 13-2Hybridization Based Approaches
- Track 13-3Sequence Based Approaches
- Track 13-4Microarrays used to Determine the Gene Expression
- Track 13-5Determing Functional Elements of Genome
- Track 14-1Comphrension of Cell Signalling Networks
- Track 14-2Theoretical Models of Signal Transduction
- Track 14-3Subcellular Targeting Mechanism
- Track 14-4Alternations in Protein Networks
- Track 14-5Comparison of Multiple Gene Regulations
- Track 14-6Functional Interpretation of Gene
Viruses show different morphologies in their shapes and sizes. These are smaller in structures than the bacteria. These are simpler as an individual, but when formed as a group they are exceptionally diverse both in replication strategies and structures. Many viruses are important human pathogens. Many techniques such as x-ray crystallography, NMR and cryo-EM are used to determine viral structures. These structure in-turns are used to develop anti-viral drugs and vaccines.
- Track 15-1Solution NMR Spectroscopy
- Track 15-2Cryo-electron Tomography
- Track 15-3X-ray Crystallography for Viruses
- Track 15-4Foci Formation
- Track 15-5Hemagglutination
- Track 15-6Plague Assay
In Genomics a cell contains complete set of DNA. In functional genomics role of genes has been identified by gene which are under expression and overexpression. Proteomics is the complete set of proteins found in a cell. Proteomics and Genomics can analyse the identification and characterization of risk factors and therapeutic targets at molecular level. In proteomics key technologies used is 2-S electrophoresis, mass spectrometry, chromatography and protein expression system. In genomics contain complete set of instructions for the construction, initiation, maintenance, operation and repair of all living cells. Genomics studies shows the structure, function and interaction of all genes that analyses to improve the diagnosis and prevention of disease. Functional Genomics in the field of molecular biology that used to describe the Genome sequencing projects and RNA sequencing to describe the gene functions and their interactions. Structural Genomics mainly analysed on the aspects of gene transcription, translation, regulation of gene expression, and protein-protein interaction in the genome such as DNA sequence and DNA structure.
- Track 16-1Function of Genomics
- Track 16-2Analysis of Genomics
- Track 16-3Clinical Proteomics
- Track 16-4Characterizes the Proteins
- Track 16-5Structural Proteomics
- Track 16-6Functional Proteomics
- Track 16-7Expression Proteomics
- Track 16-8Mapping
- Track 16-9Sequencing
Genetic Regulatory Networks process that describes the genes, proteins and small molecules which shows interactions to control the rate of transcription. Genetic Regulatory Network shows interaction in both unicellular organism and multicellular organism. In unicellular organism like yeast, which regulatory network shows response to the environment to make the cell survival. In multicellular organism regulatory network shows to control transcription, cell signalling and development. Genetic Regulatory Network control system used to regulate the thousands of gene expression in development process. These control systems contain genome as logical processing system, network substructure and reengineering the genomic control system.
- Track 17-1Mutually Interacts to Control Rate of Transcription
- Track 17-2Regulatory Networks Control Cell Signalling
- Track 17-3Reengineering Genomic Control Systems
- Track 17-4Activate Transcription Factor of Proteins
Synthetic biology is a combination of biology and engineering. Synthetic biology combines various disciplines to build artificial biological systems for research, engineering, and medical application. It is the draft and construction of new biological entities or the redesign of existing biological systems. It is the combination of advances in chemistry, biology, computer science and engineering that enables us to design a product faster, cheaper and with great precision. It is used in many applications like cell transformation, designing proteins, information storage, material production, space exploration, bio-sensors and synthetic life.
- Track 18-1Synthetic Transcription Factors
- Track 18-2Modular Protein Assembly
- Track 18-3DNA Synthesis
- Track 18-4Modeling
Molecular biophysics is a quickly evolving discipline in research that combines the concepts in physics, chemistry, engineering, mathematics, and biology. It explains the biological function in terms of molecular structure, structure organization and dynamic behaviour at many levels of complexity. It contains the measurement of molecular forces, molecular associations, allosteric interaction, and cable theory. There are many spectroscopy techniques, which is used to understand the structure of important biomolecules and inter-molecular interaction. The molecular simulation gives the microscopic structure with the help of molecular dynamics software. For more accuracy and biological relevance's, additional terms can be added to the computer simulation equation.
- Track 19-1Spectroscopy in Molecular Biophysics
- Track 19-2Molecular Simulations in Molecular Biophysics
- Track 19-3Molecular Association and Measurement of Molecular Forces
- Track 19-4Biophysical Profile
Molecular biology that concerns with the molecular basis of biological activity between biomolecules in the various system of cells including the interactions between DNA, RNA, Proteins and their biosynthesis and as well as the regulation of these interactions. Molecular Cell Biology concentrates on the macromolecules and reactions studied by biochemists, the processes described by cell biologists, and the gene control pathways identified by molecular biologists and geneticists. In this millennium, two gathering forces will reshape molecular cell biology: genomics, the complete DNA sequence of many organisms, and proteomics, a knowledge of all the possible shapes and functions that proteins .All the concepts of molecular cell biology continue to be derived from experiments, and powerful experimental tools that allow the study of living cells and organisms at higher and higher levels of resolution are being developed constantly.
- Track 20-1Gene Sequencing changes
- Track 20-2DNA Microarrays
- Track 20-3Recombinant DNA Technology
- Track 20-4Differential gene expression
- Track 20-5Metabolic proteins