Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry
NMR is a method used to obtain information about the structure and dynamics of proteins, nucleic acids, and their complexes. Structure determination by NMR spectroscopy consists of several phases, where each phase has a separate set of highly specialized techniques. The samples are prepared, measured, suitable methods are applied, and the structure is calculated and validated. NMR depends upon the quantum mechanical properties of a nucleus of an atom. Currently, most of the samples are tested in a solution like water, but researchers are going on to work with solid samples too. It is an analytical technique that ionizes chemical species and classifies the ions based on their mass to charge ratio. It measures the masses within a sample.
Mass spectrometry is used in many fields and is applied to pure samples as well as complex mixtures. Mass Spectrometry is used in both qualitative and quantitative ways. This technique is used to identify the unknown compounds, determining the isotopic composition of elements in a molecule and determining the structure of a compound by observing its fragmentation. Some of the applications are trace gas analysis, pharmacokinetics, protein characterization, space exploration, respired gas monitor and preparative mass spectrometry.
- Track 1-1 Solid State Nuclear Magnetic Spectroscopy
- Track 2-2 Multi-dimensional Spectroscopy
- Track 3-3 Fourier Transform Spectroscopy
- Track 4-4 Correlation Spectroscopy
- Track 5-5 Biomolecular NMR Spectroscopy