Transcriptomics is the study of complete set of RNAs which genome encoded in a specific organism under specific set of conditions. Transcriptomics studies shows expression profiling which examines the expression level of MRNAs in each cell by using microarray technology. In transcriptomics the expression level of each transcript changed during drug development process. Technologies used in transcriptomics is hybridization-based approach and sequence-based approaches. Hybridization-based approaches used in two microarray techniques like two-channel microarray and one-channel microarray. Two-channel microarray has two samples with different fluorescent dye. One-channel microarray is based on RNA which has labelled with fluorescent dye and hybridized with single array where millions of copies of all known genes. Hybridization-based approaches used to provide the view of gene expression by changing two or more biological conditions.
- Track 1-1 Includes Set of All RNA Molecules
- Track 2-2 Hybridization Based Approaches
- Track 3-3 Sequence Based Approaches
- Track 4-4 Microarrays used to Determine the Gene Expression
- Track 5-5 Determing Functional Elements of Genome